Having recently gotten the Incra LS router table positioner, I decided to try it out on some 1/4 sawn red oak I picked up a few months back at a saw mill I like to go to in Huntsville. I've seen a number of these machinist style tool chests and decided to try my hand.
The case is assembled with 1/2 blind DTs which were technically perfect with the LS, but still ugly IMO so I covered them over with some ~ 1/8" molding.
The drawers are also 1/2 blind DTs on the front and through DTs on the back. Splines glued into dados in the case act as guides/slides for the drawers and are positioned so that the front ends of the splines meet the end of the grooves in the drawer sides to stop the drawer with the face flush to the case of the chest.
The hardware is all pretty easy to find stuff at the box store with the little bitty knobs for the drawers being the most difficult thing to find.