Aaron, I have left most of the Files selections the default ones. The only one that is different on my machine at home is Models which I have set to F:\SKP\. I have a second HD on my computer which has a folder called SKP to store SketchUp files in. The default Windows directory for Models is the My Documents folder which is just fine, too.
As for colors, I have sky and ground turned off and the background color set to white. I'll change those settings on a case by case basis when I am ready to export images. I prefer to work with those things turned off, though.
Irony: The opposite of Wrinkly